Decoding the clinical significance of DNA variants is complex and challenging when clinical laboratories operate in silos. Sharing variant interpretations across laboratories improves accurate diagnoses and the management of patients’ health.
Shariant is a system for real-time national sharing of this vital data between Australian laboratories and clinical services. The rapid exchange of this key information allows genomic experts to decode the human genome with greater accuracy.
Importantly, it supports a process to automatically identify and resolve discrepancies in variant interpretation. Shariant also facilitates the sharing of variant interpretations internationally.
As of June 2021, Shariant has more than 7000 prospective variant interpretations from 10 clinical genetic testing laboratories across four states. Nine laboratories from another three states are in the process of joining.