When Virtual seminar on Tuesday 17 June 2025, 9am – 9.55am (AEST)
Where Online. Link will be provided in the registration confirmation email.
Registration Registration is free and available here.
Join Australian Genomics’ final DNA dialogue seminar. Professor Heidi Rehm, Professor of Pathology, Mass General Hospital and the Broad Institute of MIT and Harvard University, returns to present “Tackling the VUS problem”.
As genetic testing and the content of each test has expanded, so has the rate of Variants of Uncertain Significance (VUS). Tackling this bold challenge will require innovative efforts in building and aggregating evidence for classifying variants, improving knowledge bases, evolving standards for variant classification, and reconsidering when and how we report VUSs. This talk will touch on various aspects of this bold challenge and how we, as a community, will tackle these challenges collaboratively.
About the speaker
Professor Heidi Rehm is an investigator in the Center for Genomic Medicine at MGH, Co-Director of the Program in Medical and Population Genetics at the Broad Institute as well as the Chief Medical Officer at Broad Clinical Laboratories. She is a principal investigator of ClinGen and gnomAD, providing resources to support the interpretation of genes and variants. Rehm co-leads the Broad Center for Mendelian Genomics and the Matchmaker Exchange focused on discovering causes of rare disease. She is a strong advocate and pioneer of open science and data sharing, working to extend these approaches as chair of the Global Alliance for Genomics and Health.
About DNA dialogue
With the wealth of genomic expertise internationally, this seminar series is a forum for members of the genomics community in Australia and beyond to learn of new developments in health genomics, and the overseas experience.
The topics are diverse, including data sharing, ethics, carrier screening, cancer genomics, genomics in emerging health systems, and more.
DNA dialogue seminars are held live via zoom and registration is open to anyone working in, or impacted by, medical genomics.
Catch up on past seminars, featuring speakers from across the globe, on the Australian Genomics YouTube channel.